Biopsy proteome-based classification of T cell-mediated kidney allograft rejection

Thus, GNB4 and PDK1 in immune cells and macrophages have been identified as a potential target for further extensive studies. If their relevance were to be confirmed in a larger patient cohort, their IHC analysis could serve as an extension of established histopathological classification in the context of kidney transplant rejection.

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Publication Details

Journal
Journal of Translational Medicine
Published
2025-10-21
DOI
https://doi.org/10.1186/s12967-025-07116-8
Primary Topic
Renal Transplantation Outcomes and Treatments
Type
article
Field-Weighted Citation Impact
0.00

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Biopsy proteome-based classification of T cell-mediated kidney allograft rejection

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Biopsy proteome-based classification of T cell-mediated kidney allograft rejection

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article en

Abstract

Thus, GNB4 and PDK1 in immune cells and macrophages have been identified as a potential target for further extensive studies. If their relevance were to be confirmed in a larger patient cohort, their IHC analysis could serve as an extension of established histopathological classification in the context of kidney transplant rejection.

Journal of Translational MedicineVol. 23(1)
Medical University of Warsaw (PL), National Institute of Oncology (HU), The Maria Sklodowska-Curie National Research Institute of Oncology (PL), Institute of Bioorganic Chemistry, Polish Academy of Sciences (PL), Gdańsk Medical University (PL)
Narodowym Centrum Nauki, Gdański Uniwersytet Medyczny
Openalex Percentile: Top 54%
Renal Transplantation Outcomes and Treatments
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