Investigation of Isthmin-1 level in patients with polycystic ovary syndrome
Elevated serum ISM1 levels and their correlation with insulin resistance suggest that ISM1 may contribute to the metabolic pathophysiology of PCOS. Although its diagnostic performance is limited due to low sensitivity, ISM1 may serve as a supportive biomarker in identifying metabolic risk in women with PCOS. Further large-scale and mechanistic studies are needed to validate these findings and clarify the functional role of ISM1.
Authors
- Ahmet Burak Gürpınar (ORCID: https://orcid.org/0000-0003-3227-4682)
- Büşra Şahin (ORCID: https://orcid.org/0000-0001-5949-3143)
- Burcu Özata (ORCID: https://orcid.org/0000-0002-9960-1425)
Institutions
- Tokat Gaziosmanpaşa Üniversitesi (TR)
- Ordu University (TR)
Publication Details
- Journal
- BMC Women s Health
- Published
- 2025-10-21
- DOI
- https://doi.org/10.1186/s12905-025-03956-0
- Primary Topic
- Ovarian function and disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00