Deep learning-based approach for sperm morphology analysis

Male infertility is a highly prevalent condition throughout the world. Sperm morphology analysis(SMA) is one of most important examination for evaluating male infertility. This paper highlights the strengths, limitations, and clinical applicability of conventional machine learning (ML) models and deep learning (DL) models in SMA from various studies. Simultaneously, we explore the potential role of segmentation and classification of complete sperm structure based on deep learning algorithms. Therefore, this narrative literature review aims to summarize the current evidence of artificial intelligence and machine learning applications for sperm morphology analysis and explore further recommendations about deep learning algorithms applications to practically enhance the performance.

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Publication Details

Journal
BMC Urology
Published
2025-10-21
DOI
https://doi.org/10.1186/s12894-025-01946-w
Citations
1
Primary Topic
Sperm and Testicular Function
Type
article
Field-Weighted Citation Impact
1.70
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article

Deep learning-based approach for sperm morphology analysis

Benjamin Liang, Mingxue Wang
1 citations
BMC Urology
Sperm and Testicular Function
1.70
article

Deep learning-based approach for sperm morphology analysis

Benjamin Liang, Mingxue Wang
article en
1 citations

Abstract

Male infertility is a highly prevalent condition throughout the world. Sperm morphology analysis(SMA) is one of most important examination for evaluating male infertility. This paper highlights the strengths, limitations, and clinical applicability of conventional machine learning (ML) models and deep learning (DL) models in SMA from various studies. Simultaneously, we explore the potential role of segmentation and classification of complete sperm structure based on deep learning algorithms. Therefore, this narrative literature review aims to summarize the current evidence of artificial intelligence and machine learning applications for sperm morphology analysis and explore further recommendations about deep learning algorithms applications to practically enhance the performance.

BMC UrologyVol. 25(1)
Chongqing Emergency Medical Center (CN), First People's Hospital of Chongqing (CN), Chongqing Medical University (CN)
Openalex Percentile: Top 12%
Sperm and Testicular Function
1.70
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Deep learning-based approach for sperm morphology analysis — Benjamin Liang, Mingxue Wang · BMC Urology (2025) | TGRS Research Map | TGRS