Left-sided clear cell renal cell carcinoma initially presenting with isolated abdominal wall metastasis: a case report

Isolated abdominal wall metastasis of clear cell renal cell carcinoma is exceedingly rare. We report a case where isolated abdominal wall metastasis served as the initial manifestation while the primary renal carcinoma remained occult. The patient was admitted for a right abdominal wall mass and underwent mass excision, with postoperative pathology unexpectedly revealing metastatic clear cell carcinoma. Subsequent systematic imaging evaluation identified clear cell renal cell carcinoma in the left kidney, leading to radical left nephrectomy. This case comprehensively presents the diagnostic and therapeutic process of renal cell carcinoma with atypical site metastasis, which will enhance clinicians' ability to recognize atypical metastases of renal cell carcinoma, thereby facilitating better identification of such lesions and further guiding treatment prognosis.

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Publication Details

Journal
Discover Oncology
Published
2025-10-21
DOI
https://doi.org/10.1007/s12672-025-03741-3
Primary Topic
Renal cell carcinoma treatment
Type
article
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article

Left-sided clear cell renal cell carcinoma initially presenting with isolated abdominal wall metastasis: a case report

Ji Hyeong Yu, Minghao Yin, Zhongliang Sun, Qingyu Chen
Discover Oncology
Renal cell carcinoma treatment
article

Left-sided clear cell renal cell carcinoma initially presenting with isolated abdominal wall metastasis: a case report

Ji Hyeong Yu, Minghao Yin, Zhongliang Sun, Qingyu Chen
article en

Abstract

Isolated abdominal wall metastasis of clear cell renal cell carcinoma is exceedingly rare. We report a case where isolated abdominal wall metastasis served as the initial manifestation while the primary renal carcinoma remained occult. The patient was admitted for a right abdominal wall mass and underwent mass excision, with postoperative pathology unexpectedly revealing metastatic clear cell carcinoma. Subsequent systematic imaging evaluation identified clear cell renal cell carcinoma in the left kidney, leading to radical left nephrectomy. This case comprehensively presents the diagnostic and therapeutic process of renal cell carcinoma with atypical site metastasis, which will enhance clinicians' ability to recognize atypical metastases of renal cell carcinoma, thereby facilitating better identification of such lesions and further guiding treatment prognosis.

Discover OncologyVol. 16(1)
Nantong University (CN), The Affiliated Taizhou People's Hospital of Nanjing Medical University (CN), Nanjing Medical University (CN)
Openalex Percentile: Top 57%
Renal cell carcinoma treatment
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