Effect of Reduced Dialysate Flow on Dialysis Adequacy: A Pilot Study

Three months of Qd at 400 mL/min appears to provide similar small molecule and MM removal, but with an increase in pre-dialysis urea, creatinine, beta2-microglobulin, and myoglobin levels. Although this strategy could help preserve water, its potential impact on long-term clinical outcomes deserves further evaluation.

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Publication Details

Journal
Blood Purification
Published
2025-10-21
DOI
https://doi.org/10.1159/000549110
Primary Topic
Dialysis and Renal Disease Management
Type
article
Field-Weighted Citation Impact
0.00
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article

Effect of Reduced Dialysate Flow on Dialysis Adequacy: A Pilot Study

Claire A. Lemarchand, Mohamed Belmouaz, Pierre‐Jean Saulnier, Lisa Durocher et al.
Blood Purification
Dialysis and Renal Disease Management
article

Effect of Reduced Dialysate Flow on Dialysis Adequacy: A Pilot Study

Claire A. Lemarchand, Mohamed Belmouaz, Pierre‐Jean Saulnier, Lisa Durocher, Florence Jacomet, Laure Écotière, Sarah Ayraud-Thévenot, Jean-Philippe Devaux, Christelle Dibon, Romain Wong-Cheng, Frank Bridoux, Antoine Thierry, Jean‐Marc Gombert, Fabien dDuthe
article en

Abstract

Three months of Qd at 400 mL/min appears to provide similar small molecule and MM removal, but with an increase in pre-dialysis urea, creatinine, beta2-microglobulin, and myoglobin levels. Although this strategy could help preserve water, its potential impact on long-term clinical outcomes deserves further evaluation.

Blood PurificationVol. 55(2)
Inserm (FR), Université de Poitiers (FR), Centre Hospitalier Universitaire de Poitiers (FR), Association pour l'Utilisation du Rein Artificiel (FR)
Openalex Percentile: Top 69%
Dialysis and Renal Disease Management
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