Cervical cord atrophy correlates with intracranial lesion burden in tumefactive multiple sclerosis
During the course of TMS, early disability may be driven by a single tumefactive lesion while late disability is related to the accrual of intracranial lesions, spinal cord disease, and UCC atrophy. Across the TMS spectrum, there appears to be an inverse relationship between UCC area and ILB, partially independent of UCC lesions which trended towards statistical significance, warranting further investigation.
Authors
- Albert Aboseif (ORCID: https://orcid.org/0000-0001-5053-8544)
- Orhun H. Kantarci (ORCID: https://orcid.org/0000-0001-7038-8133)
- Matthew Kosel (ORCID: https://orcid.org/0009-0008-5787-0134)
- Burcu Zeydan (ORCID: https://orcid.org/0000-0002-2270-9868)
- Christopher G. Schwarz (ORCID: https://orcid.org/0000-0002-1466-8357)
- Paul A. Decker (ORCID: https://orcid.org/0000-0002-3756-4227)
- Jiye Son (ORCID: https://orcid.org/0000-0003-3482-9813)
- W. Oliver Tobin (ORCID: https://orcid.org/0000-0002-8141-2394)
- Caitlin S. Jackson-Tarlton
- Kejal Kantarci (ORCID: https://orcid.org/0000-0002-8001-2081)
- B. Mark Keegan (ORCID: https://orcid.org/0000-0002-2880-935X)
- Jeanette E. Eckel-Passow (ORCID: https://orcid.org/0009-0001-5176-6378)
Institutions
- Mayo Clinic (US)
- Mayo Clinic in Arizona (US)
- Mayo Clinic in Florida (US)
Publication Details
- Journal
- Journal of Neurology
- Published
- 2025-10-21
- DOI
- https://doi.org/10.1007/s00415-025-13431-3
- Primary Topic
- Multiple Sclerosis Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00