The incidence, risk factors, and outcomes of acute kidney injury after minor lower-limb amputations

AKI is a potential complication following minor lower-limb amputations. Age, COPD, diuretics, fluoroquinolones, and carbapenems were associated with increased incidence of AKI. An eGFR < 45 mL/min/1.73m<sup>2</sup>, day-1 C-reactive protein, and fluoroquinolone use were identified as independent risk factors for AKI.

Authors

Publication Details

Journal
Clinical Nephrology
Published
2025-10-21
DOI
https://doi.org/10.5414/cn111832
Primary Topic
Diabetic Foot Ulcer Assessment and Management
Type
article
Field-Weighted Citation Impact
0.00
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article

The incidence, risk factors, and outcomes of acute kidney injury after minor lower-limb amputations

Deborah Balzan, Jesmar Buttigieg, Kevin Cassar, Stefanie Marie Agius
Clinical Nephrology
Diabetic Foot Ulcer Assessment and Management
article

The incidence, risk factors, and outcomes of acute kidney injury after minor lower-limb amputations

Deborah Balzan, Jesmar Buttigieg, Kevin Cassar, Stefanie Marie Agius
article en

Abstract

AKI is a potential complication following minor lower-limb amputations. Age, COPD, diuretics, fluoroquinolones, and carbapenems were associated with increased incidence of AKI. An eGFR < 45 mL/min/1.73m<sup>2</sup>, day-1 C-reactive protein, and fluoroquinolone use were identified as independent risk factors for AKI.

Clinical NephrologyVol. 105(1)
Openalex Percentile: Top 60%
Diabetic Foot Ulcer Assessment and Management
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The incidence, risk factors, and outcomes of acute kidney injury after minor lower-limb amputations — Deborah Balzan, Jesmar Buttigieg, et al. · Clinical Nephrology (2025) | TGRS Research Map | TGRS