Gene expression reveals the pancreas of Aselli as a critical organ for plasma cell differentiation in the Eurasian common shrew

Our results support the specialized role of the pancreas of Aselli in adaptive immunity, and we propose this uniquely enlarged organ evolved at the intersection between extreme metabolic demands and high parasite burdens in tiny yet very active shrews.

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Publication Details

Journal
BMC Biology
Published
2025-10-21
DOI
https://doi.org/10.1186/s12915-025-02420-7
Primary Topic
Bat Biology and Ecology Studies
Type
article
Field-Weighted Citation Impact
0.00

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article

Gene expression reveals the pancreas of Aselli as a critical organ for plasma cell differentiation in the Eurasian common shrew

Liliana M. Dávalos, Yuanyuan Zeng, Tanya M. Lama, Dina K. N. Dechmann et al.
BMC Biology
Bat Biology and Ecology Studies
article

Gene expression reveals the pancreas of Aselli as a critical organ for plasma cell differentiation in the Eurasian common shrew

Liliana M. Dávalos, Yuanyuan Zeng, Tanya M. Lama, Dina K. N. Dechmann, Dominik von Elverfeldt, William R. Thomas, John D. Nieland, Cecilia Baldoni, Angélique Corthals
article en

Abstract

Our results support the specialized role of the pancreas of Aselli in adaptive immunity, and we propose this uniquely enlarged organ evolved at the intersection between extreme metabolic demands and high parasite burdens in tiny yet very active shrews.

BMC BiologyVol. 23(1)
University of Konstanz (DE), Smith College (US), University Medical Center Freiburg (DE), Max Planck Institute of Animal Behavior (DE), Stony Brook University (US), Aalborg University (DK), John Jay College of Criminal Justice (US)
National Science Foundation, Stony Brook University, University of Massachusetts Amherst
Openalex Percentile: Top 76%
Bat Biology and Ecology Studies
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Gene expression reveals the pancreas of Aselli as a critical organ for plasma cell differentiation in the Eurasian common shrew — Liliana M. Dávalos, Yuanyuan Zeng, et al. · BMC Biology (2025) | TGRS Research Map | TGRS