Efficacy and tolerability of a low-glycemic-index ketogenic diet in Angelman syndrome: findings from the DIANE study
While the LGID was well-tolerated and showed trends toward neurocognitive and seizure improvements, results were not statistically significant. Further studies with larger sample sizes are needed.
Authors
- Enriqueta Román‐Riechmann
- Julián Lara Herguedas
- Belén Ruíz‐Antorán (ORCID: https://orcid.org/0000-0002-2020-9077)
- Antonio F Caballero-Bermejo (ORCID: https://orcid.org/0000-0002-8113-2085)
- R Cazorla Calleja
- Carolina Gutiérrez‐Junquera (ORCID: https://orcid.org/0000-0003-0313-7072)
- Samuel Ignacio Pascual Pascual (ORCID: https://orcid.org/0000-0002-5428-8121)
- María Luz Cilleruelo Pascual
- Gema Iglesias Escalera
- María Lorenzo Ruiz
Institutions
- Universidad Nebrija (ES)
- Hospital Universitario Puerta de Hierro Majadahonda (ES)
- Universidad Alfonso X el Sabio (ES)
- Instituto de Investigación Sanitaria de Santiago (ES)
- Universidad Autónoma de Madrid (ES)
Publication Details
- Journal
- Orphanet Journal of Rare Diseases
- Published
- 2025-10-21
- DOI
- https://doi.org/10.1186/s13023-025-04037-z
- Citations
- 1
- Primary Topic
- Genetic Syndromes and Imprinting
- Type
- article
- Field-Weighted Citation Impact
- 1.82
Funders
- Universidad Complutense de Madrid