In vitro study on reversible regulation of CAR-T function by Kinsenoside
Thus, this natural occurring small molecule can act as a "functional switch," thereby providing new ideas for the balance between toxicity management and the efficacy of CAR-T therapy. Furthermore, it has the potential to pave the way for the combination of traditional Chinese medicine and modern cell therapy technology.
Authors
- Dengju Li
- Yan He (ORCID: https://orcid.org/0000-0003-2836-1767)
- Shangwu Ning
- Delian Zhou (ORCID: https://orcid.org/0009-0001-2636-8941)
- Xiaojian Zhu
- Guangmei Li
Institutions
- Hubei Provincial Center for Disease Control and Prevention (CN)
- Tongji Hospital (CN)
- Huazhong University of Science and Technology (CN)
- Hubei University (CN)
Publication Details
- Journal
- Molecular Biology Reports
- Published
- 2025-10-21
- DOI
- https://doi.org/10.1007/s11033-025-11147-1
- Primary Topic
- CAR-T cell therapy research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China