Vascular degeneration and retinal remodeling in rd10 mice: correlating OCT, OCTA, and histological findings
Overall, OCTA and IHC yielded comparable long-term vascular density results, supporting OCTA as a reliable, non-invasive tool for studying vessel degeneration in animal models. Therefore, longitudinal <i>in vivo</i> evaluation of retinal remodeling through OCT and OCTA constitutes a valuable methodology for investigating disease mechanisms and guiding therapeutic development.
Authors
- Carla Sánchez‐Castillo (ORCID: https://orcid.org/0000-0002-3697-5825)
- Oksana Kutsyr (ORCID: https://orcid.org/0000-0002-1173-6916)
- Nicolás Cuenca (ORCID: https://orcid.org/0000-0002-6767-5710)
- Xavier Sánchez‐Sáez (ORCID: https://orcid.org/0000-0001-5128-0979)
- Henar Albertos‐Arranz (ORCID: https://orcid.org/0000-0001-8656-9887)
- Laura Fernández‐Sánchez (ORCID: https://orcid.org/0000-0002-3629-0156)
- Pedro Lax (ORCID: https://orcid.org/0000-0001-6931-1008)
Institutions
- University of Alicante (ES)
- Instituto de Investigación Sanitaria y Biomédica de Alicante (ISABIAL) (ES)
Publication Details
- Journal
- Frontiers in Neuroanatomy
- Published
- 2025-10-21
- DOI
- https://doi.org/10.3389/fnana.2025.1683877
- Citations
- 1
- Primary Topic
- Retinal Development and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.81