Nano-thin amorphous tantalum-coated prosthesis for acetabular bone defect reconstruction: in vivo study and case series
<i>In vivo</i> experiments confirmed the Ta coating may contribute to enhanced osseointegration and biocompatibility of TC4-based prostheses. Meanwhile, the clinical efficacy of TC4-based Ta-coated prostheses in treating complex acetabular bone defects was satisfactory, suggesting that the tantalum coating significantly enhances osseointegration, thereby effectively improving clinical outcomes.
Authors
- Xiaofei Ma (ORCID: https://orcid.org/0000-0002-8266-2539)
- Chang Chen (ORCID: https://orcid.org/0000-0001-8286-0482)
- Siqi Wu (ORCID: https://orcid.org/0000-0001-9004-360X)
- Fuyou Wang (ORCID: https://orcid.org/0000-0001-9584-0851)
- Zhong Li (ORCID: https://orcid.org/0000-0002-1039-7000)
- Ge Chen
Institutions
- Army Medical University (CN)
- Affiliated Hospital of Southwest Medical University (CN)
- Southwest Hospital (CN)
Publication Details
- Journal
- Frontiers in Bioengineering and Biotechnology
- Published
- 2025-10-21
- DOI
- https://doi.org/10.3389/fbioe.2025.1687455
- Primary Topic
- Orthopaedic implants and arthroplasty
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China