Drug-associated serotonin syndrome in elderly patients: a comprehensive disproportionality analysis based on the FAERS database

Drug-associated serotonin syndrome risk is elevated among elderly patients. Prompt identification and discontinuation of the causative drugs are crucial for the effective management of serotonin syndrome. In clinical practice, the risk of drug-associated serotonin syndrome should be taken into account to optimize pharmacotherapy.

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Publication Details

Journal
Frontiers in Pharmacology
Published
2025-10-21
DOI
https://doi.org/10.3389/fphar.2025.1700469
Primary Topic
Electroconvulsive Therapy Studies
Type
article
Field-Weighted Citation Impact
0.00

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article

Drug-associated serotonin syndrome in elderly patients: a comprehensive disproportionality analysis based on the FAERS database

Xin Yu, D. X. Lin, Mengna Wang, Xiajiong Luo et al.
Frontiers in Pharmacology
Electroconvulsive Therapy Studies
article

Drug-associated serotonin syndrome in elderly patients: a comprehensive disproportionality analysis based on the FAERS database

Xin Yu, D. X. Lin, Mengna Wang, Xiajiong Luo, Xiaozhi Li, Xiaohua Hong, Xiaoyan Li, Zhikun Liang, Wen-Jia Chen, Hongbo Fu, Yanqiong Zhou
article en

Abstract

Drug-associated serotonin syndrome risk is elevated among elderly patients. Prompt identification and discontinuation of the causative drugs are crucial for the effective management of serotonin syndrome. In clinical practice, the risk of drug-associated serotonin syndrome should be taken into account to optimize pharmacotherapy.

Frontiers in PharmacologyVol. 16
Guiyang Medical University (CN), Sun Yat-sen University (CN), Shantou University (CN), Cancer Hospital of Shantou University Medical College (CN), Sixth Affiliated Hospital of Sun Yat-sen University (CN), Affiliated Hospital of Guizhou Medical University (CN), Second Affiliated Hospital of Shantou University Medical College (CN), The First Affiliated Hospital, Sun Yat-sen University (CN)
Sun Yat-sen University
Openalex Percentile: Top 64%
Electroconvulsive Therapy Studies
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Drug-associated serotonin syndrome in elderly patients: a comprehensive disproportionality analysis based on the FAERS database — Xin Yu, D. X. Lin, et al. · Frontiers in Pharmacology (2025) | TGRS Research Map | TGRS