Early allergen introduction overrides allergy predisposition in offspring of horses with Culicoides hypersensitivity
We provide strong evidence in a full-sibling study that early-in-life allergen exposure, independent of maternal allergen-specific immunoglobulin, prevents <i>Culicoides</i> hypersensitivity development in individuals born to parents with an allergic phenotype.
Authors
- Sigurbjörg Torsteinsdóttir (ORCID: https://orcid.org/0000-0002-3195-4937)
- Justine Tarsillo
- Bettina Wagner (ORCID: https://orcid.org/0000-0003-2370-6324)
- Vilhjálmur Svansson (ORCID: https://orcid.org/0000-0002-3984-4441)
- Elisabeth M. Simonin (ORCID: https://orcid.org/0000-0001-9195-5061)
- Sigríður Björnsdóttir (ORCID: https://orcid.org/0000-0002-3320-5972)
- Heather Freer
Institutions
- University of Iceland (IS)
- Cornell University (US)
- New York State College of Veterinary Medicine (US)
- Icelandic Transport Authority (IS)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-10-21
- DOI
- https://doi.org/10.3389/fimmu.2025.1654693
- Citations
- 1
- Primary Topic
- Food Allergy and Anaphylaxis Research
- Type
- article
- Field-Weighted Citation Impact
- 1.62
Funders
- Harry M. Zweig Memorial Fund for Equine Research
- Háskóli Íslands