Is resective surgery cost-effective for adults with epilepsy? A cost-utility analysis in a publicly funded healthcare system
Our data inform and strengthen recommendations to prioritise referral of those with drug-refractory epilepsy to surgical centres. We provide a health economic rationale for the development and support of resective epilepsy surgery programmes across national healthcare systems.
Authors
- Judith Helen Cross (ORCID: https://orcid.org/0000-0001-7345-4829)
- John S. Duncan (ORCID: https://orcid.org/0000-0002-1373-0681)
- Jane Adcock (ORCID: https://orcid.org/0000-0001-5181-0925)
- Anna Miserocchi
- Ela Akay
- Sophia Kemmis-Betty
- Jane de Tisi (ORCID: https://orcid.org/0000-0002-7666-2268)
- Rajiv Mohanraj (ORCID: https://orcid.org/0000-0002-2559-148X)
- Nandini Mullatti
- Lucy Kinton
- Alexandra Bonnon
- Arjune Sen (ORCID: https://orcid.org/0000-0002-8948-4763)
- Sean Slaght
- Vanisha Chauhan
- Howard J. Faulkner
- Shan Ellawela
- Ramesh Chelvarajah (ORCID: https://orcid.org/0000-0001-7253-9046)
- Khalid Hamandi (ORCID: https://orcid.org/0000-0001-7116-262X)
- Besa Ziso
- Katarzyna Sieradzan
- Paul Kopanidis
- Osama Sleem
- Paul Cooper (ORCID: https://orcid.org/0000-0002-7232-3365)
- David Wonderling (ORCID: https://orcid.org/0000-0003-0315-6273)
- Ilijana Sumonja Zisakis (ORCID: https://orcid.org/0000-0003-3145-9335)
Institutions
- North Bristol NHS Trust (GB)
- University of Liverpool (GB)
- Northern Health (AU)
- Queen Elizabeth Hospital Birmingham (GB)
- Great Ormond Street Hospital (GB)
- University Hospital of Wales (GB)
- Wolfson Foundation (GB)
- Newcastle upon Tyne Hospitals NHS Foundation Trust (GB)
- Walton Centre (GB)
- University Hospital Southampton NHS Foundation Trust (GB)
- University of Manchester (GB)
- Epilepsy Research UK (GB)
- National Institute for Health and Care Excellence (GB)
- University of Oxford (GB)
- Salford Royal Hospital (GB)
- National Hospital for Neurology and Neurosurgery (GB)
- King's College Hospital (GB)
- Austin Health (AU)
- University College London (GB)
Publication Details
- Journal
- Journal of Neurology Neurosurgery & Psychiatry
- Published
- 2025-10-20
- DOI
- https://doi.org/10.1136/jnnp-2025-336197
- Primary Topic
- Epilepsy research and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institute for Health and Care Excellence
- Department of Health and Social Care