Comprehensive Clinical Insights into the Diagnosis, Management, and Interprofessional Approaches to Deep Neck Infections for Healthcare Professionals

Background: Deep neck infections (DNIs) are serious suppurative processes within the fascial planes of the neck, often originating from odontogenic or oropharyngeal sources. They pose a significant risk due to their potential for rapid progression, airway compromise, and life-threatening complications like mediastinitis and sepsis.Aim: This article provides a comprehensive clinical overview of DNIs for healthcare professionals, covering etiology, epidemiology, pathophysiology, diagnostic evaluation, and evidence-based management strategies to improve patient outcomes.Methods: The review synthesizes current medical knowledge, highlighting that DNIs are typically polymicrobial, involving oral flora such as streptococci, staphylococci, and anaerobes. Diagnosis relies on a high clinical suspicion based on history and physical exam, confirmed primarily with contrast-enhanced computed tomography (CECT) to localize abscesses and define anatomical extent. Laboratory markers like elevated neutrophil-to-lymphocyte ratio (NLR) and C-reactive protein (CRP) aid in severity assessment.Results: Management is multidisciplinary. The cornerstone treatment involves prompt administration of broad-spectrum intravenous antibiotics and timely surgical or image-guided drainage of established abscesses. Securing the airway is the paramount initial priority in cases of potential compromise.Conclusion: DNIs represent a medical emergency requiring swift diagnosis and aggressive management. A coordinated interprofessional approach is essential for successful outcomes, emphasizing early imaging, appropriate antimicrobial therapy, source control, and vigilant airway management to prevent morbidity and mortality.

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Publication Details

Journal
Egyptian Journal of Chemistry
Published
2025-10-08
DOI
https://doi.org/10.21608/ejchem.2025.400755.12004
Primary Topic
Otolaryngology and Infectious Diseases
Type
article
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article

Comprehensive Clinical Insights into the Diagnosis, Management, and Interprofessional Approaches to Deep Neck Infections for Healthcare Professionals

Mona Alanazi, Najla Awadh Sattam Alanazi, ‏Zaina Zaki Almohammed, A. Alanazi et al.
Egyptian Journal of Chemistry
Otolaryngology and Infectious Diseases
article

Comprehensive Clinical Insights into the Diagnosis, Management, and Interprofessional Approaches to Deep Neck Infections for Healthcare Professionals

Mona Alanazi, Najla Awadh Sattam Alanazi, ‏Zaina Zaki Almohammed, A. Alanazi, Bader Majed Alotaibi, Ramzi Hasan Al Hamad, Ghadah Mousa Naseeb, ‏Fatimah Tuwaileh Almasoudi, Fatmah Ali Khrami, ‏Ilham Muhammad Albalawi
article en

Abstract

Background: Deep neck infections (DNIs) are serious suppurative processes within the fascial planes of the neck, often originating from odontogenic or oropharyngeal sources. They pose a significant risk due to their potential for rapid progression, airway compromise, and life-threatening complications like mediastinitis and sepsis.Aim: This article provides a comprehensive clinical overview of DNIs for healthcare professionals, covering etiology, epidemiology, pathophysiology, diagnostic evaluation, and evidence-based management strategies to improve patient outcomes.Methods: The review synthesizes current medical knowledge, highlighting that DNIs are typically polymicrobial, involving oral flora such as streptococci, staphylococci, and anaerobes. Diagnosis relies on a high clinical suspicion based on history and physical exam, confirmed primarily with contrast-enhanced computed tomography (CECT) to localize abscesses and define anatomical extent. Laboratory markers like elevated neutrophil-to-lymphocyte ratio (NLR) and C-reactive protein (CRP) aid in severity assessment.Results: Management is multidisciplinary. The cornerstone treatment involves prompt administration of broad-spectrum intravenous antibiotics and timely surgical or image-guided drainage of established abscesses. Securing the airway is the paramount initial priority in cases of potential compromise.Conclusion: DNIs represent a medical emergency requiring swift diagnosis and aggressive management. A coordinated interprofessional approach is essential for successful outcomes, emphasizing early imaging, appropriate antimicrobial therapy, source control, and vigilant airway management to prevent morbidity and mortality.

Egyptian Journal of ChemistryVol. 0(0)
National Guard Health Affairs (SA)
Openalex Percentile: Top 65%
Otolaryngology and Infectious Diseases
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