Immune checkpoint-based biomarkers for therapeutic response in patients with multiple sclerosis
These findings highlight that specific immune cell subpopulations and their IC expression profiles can serve as valuable, early, and minimally invasive immunological markers for predicting therapeutic response in MS patients.
Authors
- María Gutiérrez‐Fernández (ORCID: https://orcid.org/0000-0002-6615-4729)
- Inmaculada Puertas (ORCID: https://orcid.org/0000-0002-9567-1274)
- Rafael Gallego (ORCID: https://orcid.org/0000-0002-7260-0940)
- Eduardo López‐Collazo (ORCID: https://orcid.org/0000-0003-1957-877X)
- Beatriz Chamorro
- Jaime Valentín‐Quiroga (ORCID: https://orcid.org/0000-0001-5853-4636)
- Gabriel Torres Iglesias (ORCID: https://orcid.org/0000-0001-6479-731X)
- Laura Otero‐Ortega (ORCID: https://orcid.org/0000-0001-8765-6341)
- Fernando Laso-García (ORCID: https://orcid.org/0000-0002-5481-0514)
- MariPaz López-Molina (ORCID: https://orcid.org/0000-0002-9171-2606)
- Javier Pozo-Novoa
- Exuperio Díez-Tejedor
- Gonzalo Sáenz de Santa María-Diez
Institutions
- Hospital Universitario La Paz (ES)
- Hospital La Paz Institute for Health Research (ES)
- Centro de Investigación Biomédica en Red (ES)
- Centro de Investigación Biomédica en Red de Cáncer (ES)
- Universidad Autónoma de Madrid (ES)
- Universidad Europea de Madrid (ES)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-10-20
- DOI
- https://doi.org/10.3389/fimmu.2025.1694021
- Citations
- 2
- Primary Topic
- Multiple Sclerosis Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 2.94
Funders
- European Commission
- Instituto de Salud Carlos III