Real-world feasibility of co-administration of RSV, COVID-19, and influenza vaccines in older adults: a VAERS-based analysis

The overall safety profile of co-administered RSV, COVID-19, and influenza vaccines in older adults is favorable, with most AEFIs being expected and self-limiting. It is crucial to emphasize that this study is hypothesis-generating; the findings do not prove any causal association between vaccines and the reported adverse events. The potential signals of rare but high-risk events, such as neurological, psychiatric, and cardiovascular complications, must be investigated and confirmed in robust observational studies. Enhanced long-term surveillance is recommended to further understand these potential risks.