Comparative evaluation of hypoxia preconditioned serum (HPS) and platelet-rich plasma (PRP) on preadipocyte survival and adipogenic differentiation
These findings suggest that HPS enhance the proliferation, survival, and differentiation of preadipocytes. Validation in <i>in vivo</i> models and clinical studies will be necessary to confirm its potential efficacy in enhancing graft survival and volume retention.
Authors
- Lynn Röper (ORCID: https://orcid.org/0009-0003-0329-6695)
- Sarah Alageel
- Arndt F. Schilling (ORCID: https://orcid.org/0000-0001-7022-1069)
- Philipp Moog (ORCID: https://orcid.org/0000-0001-5002-8149)
- Ulf Dornseifer (ORCID: https://orcid.org/0000-0002-7241-8583)
- Samuel A. Knoedler (ORCID: https://orcid.org/0000-0001-5798-8003)
- Haydar Kükrek (ORCID: https://orcid.org/0000-0002-2340-2489)
- Marc Hanschen (ORCID: https://orcid.org/0000-0002-2683-9870)
- Jun Jiang (ORCID: https://orcid.org/0000-0001-7078-3715)
- Vincent Steinbacher
- Hans-Günther Machens
- Michael Martin
Institutions
- King Faisal Specialist Hospital & Research Centre (SA)
- TUM Klinikum (DE)
- Universitätsmedizin Göttingen (DE)
- Technical University of Munich (DE)
Publication Details
- Journal
- Frontiers in Bioengineering and Biotechnology
- Published
- 2025-10-20
- DOI
- https://doi.org/10.3389/fbioe.2025.1683899
- Primary Topic
- Adipose Tissue and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.00