A Novel Municipal-Level Approach to Uncover the Hidden Burden of Hepatitis C: A Replicable Model for National Elimination Strategies
This is the first Italian study to apply a standardized municipal-level classification to quantify the hidden burden of HCV. The model identifies underdiagnosed areas, highlights urban-rural disparities (a higher degree of underdiagnosis in rural areas versus a higher frequency of late diagnosis in urban ones), and provides a replicable tool for precision public health. Its adoption could enhance national HCV elimination efforts by supporting targeted screening, optimized resource allocation, and equitable access to care.
Authors
- Giuseppe D’Adamo
- Mario Masarone (ORCID: https://orcid.org/0000-0003-0550-8201)
- Chiara D’Amore
- Marcello Persico (ORCID: https://orcid.org/0000-0002-1399-6498)
- Silvana Mirella Aliberti (ORCID: https://orcid.org/0000-0003-3462-6151)
- Michele Gambardella (ORCID: https://orcid.org/0000-0002-1840-1350)
- Guido Manzi (ORCID: https://orcid.org/0009-0009-2927-3380)
- Pietro Torre (ORCID: https://orcid.org/0000-0001-8245-5305)
- Mario Capunzo (ORCID: https://orcid.org/0000-0002-2399-2650)
- Michelina Festa (ORCID: https://orcid.org/0009-0006-4551-2589)
- Antonella Santonicola (ORCID: https://orcid.org/0000-0001-9094-765X)
- Tommaso Sarcina
Institutions
- University of Salerno (IT)
- Hôpital Saint-Luc (CA)
- Ospedali Riuniti Umberto I (IT)
Publication Details
- Journal
- Viruses
- Published
- 2025-10-19
- DOI
- https://doi.org/10.3390/v17101392
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00