Investigating the Therapeutic Benefits of Cardamonin: A Comprehensive Analysis

Abstract: Cardamonin, a chalconoid derived from plants, has long been recognized for its beneficial effects on human health. Cardamonin is a chalcone derived from the "Alpinia katsumadai Hayata" plant and is useful in treating various cancers, including gastric cancer, colon cancer, myeloma, breast cancer, etc. It regularizes the immune system, reduces inflammation, and destroys microorganisms. Cardamonin promotes cell-killing signals that can cause apoptosis in abnormal or malignant cells, inhibiting cancer growth by modifying signal transduction pathways. Additionally, cardamonin stops cell growth by changing the expression of regulatory proteins during the development of cancerous cells. Due to its cytotoxic action,cardamonin is used as a new investigational cytotoxic or anticancer agent. According to current studies, cardamonin can be utilized as a multi-target therapeutic agent by targeting transcription factors, enzymes, cytokines, and various signaling molecules, including mTOR, COX-2, Wnt/-Catenin, NF-κB, and Akt. Cardamonin has a favorable pharmacokinetic and pharmacodynamic profile, making it a relatively secure biomolecule for use in the creation of pharmaceutical drugs.