Association of folate metabolism gene polymorphisms with autism susceptibility and symptom severity in the Chinese population
Most children with ASD carry deleterious variants in folate metabolism-related pathways. <i>MTHFR</i> C677T and <i>MTRR</i> A66G mutations are significantly associated with ASD.
Authors
- Lan Guo (ORCID: https://orcid.org/0000-0002-5213-2158)
- Fang Hou (ORCID: https://orcid.org/0000-0002-5574-9890)
- Li Li (ORCID: https://orcid.org/0000-0003-2342-3658)
- Ciyong Lu (ORCID: https://orcid.org/0000-0003-4266-4967)
- Caiyun Zhang (ORCID: https://orcid.org/0000-0002-9570-0207)
- Yanzhi Li (ORCID: https://orcid.org/0000-0001-7436-2440)
- Cai‐Xia Zhang (ORCID: https://orcid.org/0000-0001-9671-9412)
- Wanxin Wang (ORCID: https://orcid.org/0000-0003-4979-9514)
- Yanlin Chen (ORCID: https://orcid.org/0000-0003-1323-3826)
Institutions
- Sun Yat-sen University (CN)
Publication Details
- Journal
- World Journal of Psychiatry
- Published
- 2025-09-26
- DOI
- https://doi.org/10.5498/wjp.v15.i10.108776
- Primary Topic
- Autism Spectrum Disorder Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Key Research and Development Program of China