Systemic Sclerosis–Associated Myopathy in a Large Single‐Center Cohort: Autoantibody Profiles, Histologic Features, and Independent Risk of Death

Skeletal myopathy in SSc is associated with distinct clinical and autoantibody profiles, as well as independently increased risk of death. These findings highlight the importance of early detection and further investigation into how myopathy predicts patient outcomes, with the goal of improving targeted therapies and survival in this high-risk population.

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Publication Details

Journal
Arthritis Care & Research
Published
2025-10-20
DOI
https://doi.org/10.1002/acr.25672
Primary Topic
Systemic Sclerosis and Related Diseases
Type
article
Field-Weighted Citation Impact
0.00
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article

Systemic Sclerosis–Associated Myopathy in a Large Single‐Center Cohort: Autoantibody Profiles, Histologic Features, and Independent Risk of Death

Caoilfhionn M Connolly, Laura K. Hummers, Julie J. Paik, Fredrick M. Wigley
Arthritis Care & Research
Systemic Sclerosis and Related Diseases
article

Systemic Sclerosis–Associated Myopathy in a Large Single‐Center Cohort: Autoantibody Profiles, Histologic Features, and Independent Risk of Death

Caoilfhionn M Connolly, Laura K. Hummers, Julie J. Paik, Fredrick M. Wigley
article en

Abstract

Skeletal myopathy in SSc is associated with distinct clinical and autoantibody profiles, as well as independently increased risk of death. These findings highlight the importance of early detection and further investigation into how myopathy predicts patient outcomes, with the goal of improving targeted therapies and survival in this high-risk population.

Arthritis Care & Research
Johns Hopkins University (US), Johns Hopkins Medicine (US)
Openalex Percentile: Top 58%
Systemic Sclerosis and Related Diseases
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Systemic Sclerosis–Associated Myopathy in a Large Single‐Center Cohort: Autoantibody Profiles, Histologic Features, and Independent Risk of Death — Caoilfhionn M Connolly, Laura K. Hummers, et al. · Arthritis Care & Research (2025) | TGRS Research Map | TGRS