An Analysis of the Chemical and Physical Properties of a Silver Carboxylate Titanium-Dioxide Polydimethylsiloxane Antimicrobial Matrix on Orthopedic Implant Materials
Consistent with previous work, the 10× AgCar coating demonstrated the best results for inhibitory behavior on two distinct fronts: mechanically, through roughness and increased hydrophobicity, and chemically, through AgCar elution activity. Furthermore, the 10× coating will likely not impair the durability or elasticity of the implant within the body or silicone prosthetic liners. Thus, the 95% TiO<sub>2</sub>:5% PDMS matrix doped with a 10× AgCar concentration is a prime candidate for clinical application consideration.
Authors
- Dominique M. Dockery (ORCID: https://orcid.org/0000-0001-5756-5019)
- Christopher T. Born (ORCID: https://orcid.org/0000-0002-1402-683X)
- Odelia Cooper (ORCID: https://orcid.org/0000-0001-5955-8242)
- Valentin Antoci (ORCID: https://orcid.org/0000-0001-8490-2690)
- José‐Tomás Navarro (ORCID: https://orcid.org/0000-0001-9101-6013)
- Sai Allu (ORCID: https://orcid.org/0000-0002-0288-4503)
- Dioscaris Garcia (ORCID: https://orcid.org/0000-0002-9001-6262)
- Neel Vishwanath (ORCID: https://orcid.org/0000-0003-2496-9687)
- Nayoung Kim (ORCID: https://orcid.org/0000-0002-9397-0406)
- R.J.I. Bain
Institutions
- Brown University (US)
- Rhode Island Hospital (US)
Publication Details
- Journal
- Surgical Infections
- Published
- 2025-10-20
- DOI
- https://doi.org/10.1177/10962964251389154
- Primary Topic
- Bone Tissue Engineering Materials
- Type
- article
- Field-Weighted Citation Impact
- 0.00