A Case of Ruptured Posterior Inferior Cerebellar Artery Aneurysm Suggestive of Dissection in an Octogenarian Patient with Anti-Neutrophil Cytoplasmic Antibody-Related Vasculitis

An anti-neutrophil cytoplasmic antibody-associated vasculitis is a systemic autoimmune disease characterized by small-vessel inflammation, with rare central nervous system manifestations such as subarachnoid hemorrhage. Cerebral artery dissection, a rare but serious condition that can lead to ischemic stroke or subarachnoid hemorrhage, predominantly affects young to middle-aged adults and is less common in elderly patients. We report the case of an 86-year-old male with anti-neutrophil cytoplasmic antibody-associated vasculitis who developed subarachnoid hemorrhage due to a ruptured posterior inferior cerebellar artery aneurysm, suggestive of dissection. Despite diagnostic challenges related to the patient's advanced age, repeated vascular imaging indicated arterial dissection, and parent artery occlusion successfully prevented re-rupture. This case highlights the importance of considering cerebral artery dissection as a potential cause of subarachnoid hemorrhage in patients with anti-neutrophil cytoplasmic antibody-associated vasculitis, even in octogenarians, and underscores the need for comprehensive vascular evaluation to ensure timely diagnosis and management.

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Journal
NMC Case Report Journal
Published
2025-09-25
DOI
https://doi.org/10.2176/jns-nmc.2025-0004
Primary Topic
Vasculitis and related conditions
Type
article
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article

A Case of Ruptured Posterior Inferior Cerebellar Artery Aneurysm Suggestive of Dissection in an Octogenarian Patient with Anti-Neutrophil Cytoplasmic Antibody-Related Vasculitis

Fumitaka Miya, T Ichikawa, Tomoki Ishigaki, Masashi Fujimoto et al.
NMC Case Report Journal
Vasculitis and related conditions
article

A Case of Ruptured Posterior Inferior Cerebellar Artery Aneurysm Suggestive of Dissection in an Octogenarian Patient with Anti-Neutrophil Cytoplasmic Antibody-Related Vasculitis

Fumitaka Miya, T Ichikawa, Tomoki Ishigaki, Masashi Fujimoto, Takenori Sato, Takuya Yamanaka, Hiroshi Tanemura, Ryo Ishikawa
article en

Abstract

An anti-neutrophil cytoplasmic antibody-associated vasculitis is a systemic autoimmune disease characterized by small-vessel inflammation, with rare central nervous system manifestations such as subarachnoid hemorrhage. Cerebral artery dissection, a rare but serious condition that can lead to ischemic stroke or subarachnoid hemorrhage, predominantly affects young to middle-aged adults and is less common in elderly patients. We report the case of an 86-year-old male with anti-neutrophil cytoplasmic antibody-associated vasculitis who developed subarachnoid hemorrhage due to a ruptured posterior inferior cerebellar artery aneurysm, suggestive of dissection. Despite diagnostic challenges related to the patient's advanced age, repeated vascular imaging indicated arterial dissection, and parent artery occlusion successfully prevented re-rupture. This case highlights the importance of considering cerebral artery dissection as a potential cause of subarachnoid hemorrhage in patients with anti-neutrophil cytoplasmic antibody-associated vasculitis, even in octogenarians, and underscores the need for comprehensive vascular evaluation to ensure timely diagnosis and management.

NMC Case Report JournalVol. 12(0)
Ise Red Cross Hospital (JP)
Openalex Percentile: Top 57%
Vasculitis and related conditions
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