Ethyl Acetate Extract from Wenxia Formula (WFEA) Attenuates Immunosuppression in Lung Cancer by Inhibiting Treg Differentiation via Blockade of TGF-Β/Smad Signaling
WFEA may regulate the growth of Tregs to modulate the immune microenvironment of the LLC model mice, indicating its potential as an anti-LLC agent.
Authors
- Dongdong Fang (ORCID: https://orcid.org/0000-0002-8556-1557)
- Shulong Jiang (ORCID: https://orcid.org/0000-0001-8034-6762)
- Bin Zheng (ORCID: https://orcid.org/0000-0002-0998-7177)
- Meng Wang (ORCID: https://orcid.org/0000-0001-7830-5216)
- Hui Li (ORCID: https://orcid.org/0000-0001-7223-5296)
- Xiangyu Han
Institutions
- Shandong University of Traditional Chinese Medicine (CN)
- Jining First People's Hospital (CN)
- Affiliated Hospital of Jining Medical University (CN)
- Jining Medical University (CN)
Publication Details
- Journal
- Current Topics in Medicinal Chemistry
- Published
- 2025-10-16
- DOI
- https://doi.org/10.2174/0115680266415173251010101905
- Citations
- 1
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 0.94