Using Mendelian Randomization to Dissect the Relationship Between High-Altitude Adaptation and Liver Diseases/Traits
In conclusion, our study provides suggestive evidence for a potentially causal bidirectional association between HAA and GGT. These novel insights may inform the development of targeted preventive measures and therapeutic interventions for liver diseases and high-altitude adaptation.
Authors
- Shilin Huang (ORCID: https://orcid.org/0000-0003-4215-9151)
- Yan Lin (ORCID: https://orcid.org/0000-0003-4384-8354)
- Ming-Gen Hu
- Qingfeng Song (ORCID: https://orcid.org/0000-0003-4314-6897)
- Tianzhun Wu (ORCID: https://orcid.org/0000-0001-6237-169X)
- Shizhou Li
- Xing Gao (ORCID: https://orcid.org/0000-0001-8893-2416)
- Jiazhou Ye (ORCID: https://orcid.org/0000-0001-9124-7284)
- Juanjuan Liu (ORCID: https://orcid.org/0000-0003-0563-4670)
- Wenfeng Luo
- Rong Liang (ORCID: https://orcid.org/0000-0001-5209-9426)
- Ruofan Li (ORCID: https://orcid.org/0009-0009-2391-8889)
- Xu Li (ORCID: https://orcid.org/0000-0003-1699-4620)
- Chaofan Shi
- Dandan Zeng
Institutions
- Guangxi Medical University (CN)
- China-Japan Friendship Hospital (CN)
- Chinese PLA General Hospital (CN)
- Qujing Normal University (CN)
- Dongguan People’s Hospital (CN)
- PLA Academy of Military Science (CN)
Publication Details
- Journal
- High Altitude Medicine & Biology
- Published
- 2025-10-17
- DOI
- https://doi.org/10.1177/15578682251385415
- Primary Topic
- High Altitude and Hypoxia
- Type
- article
- Field-Weighted Citation Impact
- 0.00