Incorporating lipoprotein (a) into patient care: Polish landscape in light of national recommendations and the updated ESC/EAS guidelines
Atherosclerotic cardiovascular disease (ASCVD) is the leading cause of death in Poland. Lipoprotein(a) [Lp(a)] constitutes an independent, causal risk factor for ASCVD and aortic valve stenosis. Elevated Lp(a) is found in approximately 20% of the Polish population. Lp(a) measurements have been recommended in all adult patients to improve cardiovascular risk stratification. As the testing rate remains insufficient, there is a need to facilitate the incorporation of Lp(a) into routine patient care. This clinically oriented review outlines (i) up-to-date evidence on the role of Lp(a) in cardiovascular diseases, (ii) recent real-world data on the characteristics of Polish patients with elevated Lp(a), and (iii) strategies for Lp(a) testing and management in light of the current national recommendations and the latest 2025 Focused Update of the 2019 ESC/EAS Guidelines for the management of dyslipidemias.
Authors
- Aleksandra Gąsecka (ORCID: https://orcid.org/0000-0001-5083-7587)
- Michał Lis (ORCID: https://orcid.org/0000-0001-7675-398X)
- Maciej Banach (ORCID: https://orcid.org/0000-0001-6690-6874)
- Jakub Michał Zimodro (ORCID: https://orcid.org/0000-0002-2405-8982)
- Grzegorz Procyk (ORCID: https://orcid.org/0000-0001-8333-7570)
- Tomasz Saniewski (ORCID: https://orcid.org/0000-0002-8088-439X)
- Olivia Wasilewska (ORCID: https://orcid.org/0009-0006-9207-4008)
- Bartosz Mroczyk
Institutions
- John Paul II Catholic University of Lublin (PL)
- Johns Hopkins University (US)
- Medical University of Warsaw (PL)
- Johns Hopkins Medicine (US)
- Medical University of Lodz (PL)
- Uczelnia Łazarskiego (PL)
- Central Clinical Hospital (PL)
Publication Details
- Journal
- Archives of Medical Science
- Published
- 2025-10-20
- DOI
- https://doi.org/10.5114/aoms/212635
- Citations
- 2
- Primary Topic
- Lipoproteins and Cardiovascular Health
- Type
- article
- Field-Weighted Citation Impact
- 4.01