Early Treatment With Curative Dose Low-Molecular-Weight Heparin (LMWH) Versus Plasmapheresis in Severe Acute Pancreatitis in Intensive Care: A Comparative Study

In this single-center observational study, therapeutic-dose LMWH was associated with improved clinical outcomes and fewer adverse events compared to plasmapheresis. These findings suggest LMWH may be a safe and effective option for managing hypertriglyceridemia-induced SAP, though randomized controlled trials are needed to confirm these results.

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Publication Details

Journal
Cureus
Published
2025-10-20
DOI
https://doi.org/10.7759/cureus.94994
Primary Topic
Pancreatitis Pathology and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Early Treatment With Curative Dose Low-Molecular-Weight Heparin (LMWH) Versus Plasmapheresis in Severe Acute Pancreatitis in Intensive Care: A Comparative Study

Ophyr Mourad, Ayadi Yacine, Haitham Salem, Zeddam Soheib
Cureus
Pancreatitis Pathology and Treatment
article

Early Treatment With Curative Dose Low-Molecular-Weight Heparin (LMWH) Versus Plasmapheresis in Severe Acute Pancreatitis in Intensive Care: A Comparative Study

Ophyr Mourad, Ayadi Yacine, Haitham Salem, Zeddam Soheib
article en

Abstract

In this single-center observational study, therapeutic-dose LMWH was associated with improved clinical outcomes and fewer adverse events compared to plasmapheresis. These findings suggest LMWH may be a safe and effective option for managing hypertriglyceridemia-induced SAP, though randomized controlled trials are needed to confirm these results.

CureusVol. 17(10)
Hôpital Mustapha Pacha (DZ)
Openalex Percentile: Top 53%
Pancreatitis Pathology and Treatment
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