Clinical and Neuroimaging Effects of Mindfulness-Based Cognitive Therapy for Symptomatic Obsessive-Compulsive Disorder Patients after First-Line Treatments: A Randomised Controlled Trial
MBCT is an effective strategy for individuals with moderately symptomatic OCD who continue to experience symptoms despite prior gold-standard treatments. While no post-treatment changes in brain functional connectivity were observed, baseline connectivity patterns predicted symptom reduction, suggesting a neural basis for MBCT response.
Authors
- Jessica R. Andrews‐Hanna (ORCID: https://orcid.org/0000-0003-1769-6756)
- Narcı́s Cardoner (ORCID: https://orcid.org/0000-0001-9633-0888)
- Lorea Mar‐Barrutia (ORCID: https://orcid.org/0000-0002-7531-0316)
- María Alemany-Navarro (ORCID: https://orcid.org/0000-0002-8491-0137)
- Marta Cano (ORCID: https://orcid.org/0000-0003-0675-9483)
- Marina López‐Solà (ORCID: https://orcid.org/0000-0002-5517-2665)
- Marı́a J. Portella (ORCID: https://orcid.org/0000-0002-2007-9516)
- Neus Miquel-Giner
- Muriel Vicent-Gil (ORCID: https://orcid.org/0000-0001-7534-5095)
- Carles Soriano‐Mas (ORCID: https://orcid.org/0000-0003-4574-6597)
- Clara López‐Solà (ORCID: https://orcid.org/0000-0001-8104-5291)
- Joaquim Soler (ORCID: https://orcid.org/0000-0001-8077-3641)
- Maria Serra-Blasco (ORCID: https://orcid.org/0000-0001-5793-9906)
- Víctor De la Peña‐Arteaga (ORCID: https://orcid.org/0000-0001-8627-2653)
- Ignacio Martínez‐Zalacaín (ORCID: https://orcid.org/0000-0002-4036-0284)
- Daniel Porta‐Casteràs (ORCID: https://orcid.org/0000-0002-3921-3607)
- Pino Alonso (ORCID: https://orcid.org/0009-0000-1398-9821)
Institutions
- Universitat Autònoma de Barcelona (ES)
- University of Arizona (US)
- Instituto de Salud Carlos III (ES)
- Hospital de Sant Pau (ES)
- Bellvitge University Hospital (ES)
- Institut d'Investigació Biomédica de Bellvitge (ES)
- BioCruces Health research Institute (ES)
- Centro de Investigación Biomédica en Red de Salud Mental (ES)
- Departament de Salut (ES)
- Institut Català d'Oncologia (ES)
- Hospital Universitario Araba (ES)
- Osakidetza (ES)
- Parc Sanitari Sant Joan de Déu (ES)
- Instituto de Biomedicina de Sevilla (ES)
- Fundació Clínic per a la Recerca Biomèdica (ES)
- Consorci Institut D'Investigacions Biomediques August Pi I Sunyer (ES)
- Institut de Recerca Sant Pau (ES)
- Universitat de Barcelona (ES)
Publication Details
- Journal
- Psychotherapy and Psychosomatics
- Published
- 2025-10-20
- DOI
- https://doi.org/10.1159/000548961
- Primary Topic
- Obsessive-Compulsive Spectrum Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Ministerio de Ciencia, Innovación y Universidades
- European Commission
- Instituto de Salud Carlos III