Exploring Neuroinflammation and Its Role in Postoperative Cognitive Dysfunction following Spine Surgery
This study highlights potential associations between neuroinflammation and cognitive decline following spine surgery. Targeting neuroinflammatory pathways could be crucial in mitigating POCD in older patients. Biomarkers may help identify high-risk patients and guide the development of targeted interventions. .
Authors
- Jan‐Uwe Müller (ORCID: https://orcid.org/0000-0002-9342-5942)
- Klaus Hahnenkamp (ORCID: https://orcid.org/0000-0003-2905-0362)
- Sebastian Rehberg (ORCID: https://orcid.org/0000-0002-5835-7083)
- Jasmin Dilz (ORCID: https://orcid.org/0009-0006-9333-8925)
- Antje Vogelgesang (ORCID: https://orcid.org/0000-0003-2984-0831)
- Martin Weidemeier (ORCID: https://orcid.org/0000-0002-3706-6551)
- Stephan Nowak (ORCID: https://orcid.org/0000-0002-0856-6768)
- A Pohl (ORCID: https://orcid.org/0009-0009-1264-5336)
- Agnes Flöel (ORCID: https://orcid.org/0000-0002-1475-5872)
- Johanna Ruhnau (ORCID: https://orcid.org/0000-0003-0238-1305)
- Denise Sperlich
- Taras Usichenko (ORCID: https://orcid.org/0000-0002-6173-5436)
- Henry W. S. Schroeder (ORCID: https://orcid.org/0000-0002-9095-1517)
- Robert Fleischmann (ORCID: https://orcid.org/0000-0001-8159-2658)
- Johannes Ehler (ORCID: https://orcid.org/0000-0001-7866-9781)
- Jonas Müller (ORCID: https://orcid.org/0000-0002-4915-8445)
- Sarah Strack
Institutions
- Bielefeld University (DE)
- Hochschule Bielefeld (DE)
- Universitätsmedizin Greifswald (DE)
- German Center for Neurodegenerative Diseases (DE)
- Evangelisches Krankenhaus Bielefeld (DE)
- Klinikum Bielefeld (DE)
- Jena University Hospital (DE)
- Bethel University (US)
Publication Details
- Journal
- Gerontology
- Published
- 2025-10-20
- DOI
- https://doi.org/10.1159/000548923
- Citations
- 1
- Primary Topic
- Intensive Care Unit Cognitive Disorders
- Type
- article
- Field-Weighted Citation Impact
- 1.55