Comparing and combining TSPO-PET tracers in tauopathies
The pipeline was effective at harmonising TSPO-PET tracers and standardising the regional quantification of neuroinflammation in clinically matched cohorts of PSP, while the standardisation pipeline results were less robust across AD cohorts.
Authors
- Alexandra T. Strauss (ORCID: https://orcid.org/0000-0001-6313-7221)
- Maura Malpetti (ORCID: https://orcid.org/0000-0001-8923-9656)
- Tim D. Fryer (ORCID: https://orcid.org/0000-0003-1555-9790)
- Robert Perneczky (ORCID: https://orcid.org/0000-0003-1981-7435)
- John T. O’Brien (ORCID: https://orcid.org/0000-0002-0837-5080)
- James Benedict Rowe (ORCID: https://orcid.org/0000-0001-7216-8679)
- Boris‐Stephan Rauchmann (ORCID: https://orcid.org/0000-0003-4547-6240)
- Gassan Massarweh (ORCID: https://orcid.org/0000-0003-2259-9627)
- Johannes Levin (ORCID: https://orcid.org/0000-0001-5092-4306)
- Carla Palleis (ORCID: https://orcid.org/0000-0002-4331-8145)
- Nesrine Rahmouni (ORCID: https://orcid.org/0009-0004-3081-8468)
- Johannes Gnörich (ORCID: https://orcid.org/0000-0003-1554-7765)
- Franklin I. Aigbirhio (ORCID: https://orcid.org/0000-0001-9453-5257)
- Günter U. Höglinger (ORCID: https://orcid.org/0000-0001-7587-6187)
- Robert Hopewell (ORCID: https://orcid.org/0000-0002-2478-5872)
- Nicolai Franzmeier (ORCID: https://orcid.org/0000-0001-9736-2283)
- Pedro Rosa‐Neto (ORCID: https://orcid.org/0000-0001-9116-1376)
- Matthias Brendel
- Young T. Hong
- P Simon Jones
- Sebastian N. Roemer‐Cassiano
Institutions
- Montreal Neurological Institute and Hospital (CA)
- MRC Cognition and Brain Sciences Unit (GB)
- University of Cambridge (GB)
- German Center for Neurodegenerative Diseases (DE)
- Cambridge University Hospitals NHS Foundation Trust (GB)
- LMU Klinikum (DE)
- Cambridge School (PT)
- Southwestern Medical Center (US)
- Munich Cluster for Systems Neurology (DE)
- UK Dementia Research Institute (GB)
- Max Planck Institute for Human Cognitive and Brain Sciences (DE)
- Centre Intégré Universitaire de Santé et de Services Sociaux du Centre-Sud-de-l'Île-de-Montréal (CA)
- Imperial College London (GB)
- McGill University (CA)
- Ludwig-Maximilians-Universität München (DE)
- The University of Texas Southwestern Medical Center (US)
- University of Gothenburg (SE)
- University of Sheffield (GB)
Publication Details
- Journal
- European Journal of Nuclear Medicine and Molecular Imaging
- Published
- 2025-10-20
- DOI
- https://doi.org/10.1007/s00259-025-07579-3
- Primary Topic
- Alzheimer's disease research and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Biogen
- McGill University
- TauRx Pharmaceuticals
- Guarantors of Brain
- Eisai
- Novo Nordisk
- Ludwig-Maximilians-Universität München
- UK Dementia Research Institute