Genetic Liabilities to Neuropsychiatric Conditions in Suicide Deaths With No Prior Suicidality
In this cohort study, SD-N showed significantly different genetic liabilities to neuropsychiatric conditions from SD-S. Results have implications for future suicide research and prevention for persons at risk of mortality.
Authors
- Andrew Mark McIntosh (ORCID: https://orcid.org/0000-0002-0198-4588)
- Zhe Yu (ORCID: https://orcid.org/0000-0002-6908-6135)
- Erin A. Kaufman (ORCID: https://orcid.org/0000-0002-7636-6602)
- Brooks Keeshin (ORCID: https://orcid.org/0000-0002-8917-9443)
- Eric T. Monson (ORCID: https://orcid.org/0000-0002-8552-8300)
- Douglas Tharp
- Anna R. Docherty (ORCID: https://orcid.org/0000-0001-7139-7007)
- Michael Staley
- Andrey A. Shabalin (ORCID: https://orcid.org/0000-0003-0309-6821)
- Qingqin S. Li (ORCID: https://orcid.org/0000-0003-4182-4535)
- Lisa Baird
- Amanda V. Bakian (ORCID: https://orcid.org/0000-0001-6805-1160)
- Niamh Mullins (ORCID: https://orcid.org/0000-0001-8021-839X)
- Emily DiBlasi (ORCID: https://orcid.org/0000-0002-1266-7297)
- Seonggyun Han (ORCID: https://orcid.org/0000-0003-2227-4953)
- Heather C. Whalley (ORCID: https://orcid.org/0000-0002-4505-8869)
- Sarah M. C. Colbert (ORCID: https://orcid.org/0000-0003-3060-7471)
- Hilary Coon (ORCID: https://orcid.org/0000-0002-8877-5446)
- David K. Crockett
- Dierdre Amaro
Institutions
- Intermountain Healthcare (US)
- Uppsala University (SE)
- Primary Children's Hospital (US)
- University of Utah (US)
- Huntsman Cancer Institute (US)
- CHDI Foundation (US)
- MRC Centre for Regenerative Medicine (GB)
- Utah Department of Health (US)
- Janssen (United States) (US)
- The Queen's Medical Research Institute (GB)
- University of Edinburgh (GB)
- Icahn School of Medicine at Mount Sinai (US)
Publication Details
- Journal
- JAMA Network Open
- Published
- 2025-10-20
- DOI
- https://doi.org/10.1001/jamanetworkopen.2025.38204
- Primary Topic
- Suicide and Self-Harm Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- American Foundation for Suicide Prevention
- University of Utah
- National Alliance for Research on Schizophrenia and Depression
- Wellcome Trust
- Huntsman Cancer Foundation
- Huntsman Cancer Institute
- Scottish Government
- Scottish Funding Council
- National Institutes of Health
- Center for Clinical and Translational Science, University of Utah
- Chief Scientist Office, Scottish Government Health and Social Care Directorate
- Medical Research Council
- National Institute of Mental Health
- National Cancer Institute
- National Center for Advancing Translational Sciences