Metamizole-Induced Agranulocytosis: A Case Report
Metamizole, a widely used analgesic and antipyretic, has been associated with rare but potentially life-threatening hematological adverse reactions, such as agranulocytosis. This case report highlights the diagnostic complexity and clinical management of a patient who presented with neutropenic fever and concurrent multidrug-resistant infections, ultimately found to be related to metamizole-induced agranulocytosis. It underlines the importance of considering drug-induced causes in the differential diagnosis of agranulocytosis and stresses the relevance of early identification and prompt discontinuation of the causative agent.
Authors
- Maria do Rosário Ginga
- Carla Fernandes (ORCID: https://orcid.org/0000-0001-8259-6829)
- Joana Cartucho
- Ana Ruivo
- Ines Bonito
Institutions
- Administração Regional de Saúde de Lisboa e Vale do Tejo (PT)
Publication Details
- Journal
- Cureus
- Published
- 2025-10-20
- DOI
- https://doi.org/10.7759/cureus.94983
- Citations
- 1
- Primary Topic
- Blood disorders and treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.82