Predictors of aspiration, lower respiratory tract infection, and respiratory failure among individuals with Rett Syndrome: analysis of real-world claims data in the United States
Baseline neurological and respiratory disorders were common predictors of aspiration, LRTI, or RF. Additional predictors included gastrointestinal disorders for LRTI and RF; and musculoskeletal disorders for RF only. These real-world findings can help inform evidence based clinical decision-making for management of RTT.
Authors
- Krithika Rajagopalan (ORCID: https://orcid.org/0000-0002-4878-0822)
- Nazia Rashid (ORCID: https://orcid.org/0000-0002-4227-1234)
- Dilesh Doshi (ORCID: https://orcid.org/0009-0006-0970-2158)
- Daksha Gopal (ORCID: https://orcid.org/0000-0003-2710-980X)
Institutions
- Acadia Pharmaceuticals (United States) (US)
- American Society for Neurochemistry (US)
Publication Details
- Journal
- Frontiers in Pediatrics
- Published
- 2025-10-20
- DOI
- https://doi.org/10.3389/fped.2025.1681103
- Primary Topic
- Genetics and Neurodevelopmental Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- ACADIA Pharmaceuticals