Molecular Characterization of Pericardial Mesothelioma With Constrictive and Recurrent Pericarditis
MPM can closely mimic chronic inflammatory disease, and accurate diagnosis with comprehensive profiling is essential to guide targeted therapy. TAZ amplification suggests Hippo pathway as a driver of BAP-intact tumors and may serve as a predictive biomarker of mesothelial immunogenicity.
Authors
- Ryan Tudino
- Christopher G. Azzoli (ORCID: https://orcid.org/0000-0003-0136-7317)
- Katharine French
- Shelby Smith
- Liang Cheng (ORCID: https://orcid.org/0009-0004-2260-6254)
Institutions
- Rhode Island Department of Health (US)
- Brown University (US)
- Rhode Island Hospital (US)
Publication Details
- Journal
- JACC Case Reports
- Published
- 2025-10-19
- DOI
- https://doi.org/10.1016/j.jaccas.2025.105759
- Primary Topic
- Occupational and environmental lung diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00