Toxicological and nutritional evaluation of plant cell cultures from scurvy grass (Cochlearia danica) and rowan (Sorbus aucuparia)
These findings indicate that the no-observed-adverse-effect level (NOAEL) for both PCCs exceeds 2000 mg/kg. Overall, our findings indicate that the consumption of these PCCs could be considered safe and non-toxic, although further assessments on potential allergens and phytohormone accumulation are necessary to fully ensure consumer safety. This study highlights the oral safety of PCCs for consideration as a novel food ingredient and serve as a basis for evaluating toxicological impacts of PCCs.
Authors
- Felicianna
- Fangfei Zhang (ORCID: https://orcid.org/0000-0003-4806-1972)
- Hani El‐Nezami (ORCID: https://orcid.org/0000-0001-6700-4346)
- Valeria Iannone (ORCID: https://orcid.org/0000-0003-2114-1366)
- Emilia Nordlund (ORCID: https://orcid.org/0000-0003-3725-121X)
- Marjukka Kolehmainen (ORCID: https://orcid.org/0000-0002-3770-2538)
- Carlos Gómez-Gallego (ORCID: https://orcid.org/0000-0003-0219-1827)
- Heiko Rischer (ORCID: https://orcid.org/0000-0002-8004-4526)
- Natalia Rosa‐Sibakov (ORCID: https://orcid.org/0000-0003-0188-8243)
- Hoi Kit Matthew Leung (ORCID: https://orcid.org/0009-0001-6153-7245)
- Emily Kwun Kwan Lo
- Marsena Jasiel Ismaiah
- Hon Ming Cheung (ORCID: https://orcid.org/0000-0001-7608-6283)
Institutions
- University of Eastern Finland (FI)
- VTT Technical Research Centre of Finland (FI)
- University of Hong Kong (HK)
Publication Details
- Journal
- Frontiers in Toxicology
- Published
- 2025-10-20
- DOI
- https://doi.org/10.3389/ftox.2025.1655489
- Citations
- 1
- Primary Topic
- Plant tissue culture and regeneration
- Type
- article
- Field-Weighted Citation Impact
- 0.81