Impact of high-protein, low-calorie diet on anthropometric indices, glycation, and inflammation associated with the fat mass and obesity (FTO) gene among individuals with overweight/obesity

This study concludes that an HPLC diet modifies the variation of the FTO rs9939609 genotype and anthropometric measurements. These findings also suggest that high dietary protein intakes may protect against the obesogenic effects of FTO risk genotypes, leading to weight loss and improved metabolic parameters.

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Publication Details

Journal
Frontiers in Nutrition
Published
2025-10-20
DOI
https://doi.org/10.3389/fnut.2025.1619543
Citations
1
Primary Topic
Diet and metabolism studies
Type
article
Field-Weighted Citation Impact
1.16
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article

Impact of high-protein, low-calorie diet on anthropometric indices, glycation, and inflammation associated with the fat mass and obesity (FTO) gene among individuals with overweight/obesity

Sharifa AlBlooshi, Huma Naqeeb, Hayder Hasan, Ali Madi Almajwal et al.
1 citations
Frontiers in Nutrition
Diet and metabolism studies
1.16
article

Impact of high-protein, low-calorie diet on anthropometric indices, glycation, and inflammation associated with the fat mass and obesity (FTO) gene among individuals with overweight/obesity

Sharifa AlBlooshi, Huma Naqeeb, Hayder Hasan, Ali Madi Almajwal, Fahad Lodhi, Bismillah Sehar, Bibi Hajira, Falak Zeb, Muhammad Omar Malik, Sami Siraj, Iftikhar Alam, Fakhrunisa
article en
1 citations

Abstract

This study concludes that an HPLC diet modifies the variation of the FTO rs9939609 genotype and anthropometric measurements. These findings also suggest that high dietary protein intakes may protect against the obesogenic effects of FTO risk genotypes, leading to weight loss and improved metabolic parameters.

Frontiers in NutritionVol. 12
Birmingham City University (GB), Bacha Khan University (PK), Abdul Wali Khan University Mardan (PK), Khyber Medical University (PK), King Saud University (SA), University of Sharjah (AE), Dubai Medical College (AE), Zayed University (AE)
Openalex Percentile: Top 17%
Diet and metabolism studies
1.16
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Impact of high-protein, low-calorie diet on anthropometric indices, glycation, and inflammation associated with the fat mass and obesity (FTO) gene among individuals with overweight/obesity — Sharifa AlBlooshi, Huma Naqeeb, et al. · Frontiers in Nutrition (2025) | TGRS Research Map | TGRS