LncRNA NRIR inhibits osteogenesis by promoting macrophage M1 polarization through RSAD2/NF-κB axis in peri-implantitis
This study demonstrates that <i>NRIR</i> functions as a pro-inflammatory modulator in peri-implantitis by activating M1 macrophages through the <i>RSAD2</i>/NF-κB axis, providing novel insights into peri-implantitis pathogenesis that may inform future preventive and therapeutic strategies.
Authors
- Qiqi Liu (ORCID: https://orcid.org/0000-0001-7677-9901)
- Yang Zhou (ORCID: https://orcid.org/0000-0001-5199-156X)
- Rongjie Zhao (ORCID: https://orcid.org/0000-0002-1571-1185)
- Ke Yu
- Lan Wang
- Keming Xiao
Institutions
- Southwest Medical University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-10-20
- DOI
- https://doi.org/10.3389/fimmu.2025.1650984
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 0.00