Efficacy and safety of idebenone tablets in patients with post-stroke cognitive impairment: a real-world study
This real-world study suggests that three-month idebenone therapy provides meaningful improvements in cognitive function among patients with post-stroke cognitive impairment, with excellent safety and adherence profiles. However, the observational, single-arm design without a control group means that observed improvements cannot be definitively attributed to the intervention alone. Further randomized controlled trials are warranted to confirm these findings and optimize treatment protocols.
Authors
- Yi Xie (ORCID: https://orcid.org/0000-0001-8095-4856)
- Yanqi Shao
- Zunchun Xie
- Shunyuan Guo (ORCID: https://orcid.org/0000-0003-2945-0366)
- Xinyu Zhao (ORCID: https://orcid.org/0009-0000-7291-7158)
Institutions
- Nanchang University (CN)
- The Central Hospital of Enshi Tujia and Miao Autonomous Prefecture (CN)
- Zhejiang Provincial People's Hospital (CN)
- First Affiliated Hospital of Zhengzhou University (CN)
- First Affiliated Hospital of Nanchang University (CN)
Publication Details
- Journal
- Frontiers in Neurology
- Published
- 2025-10-20
- DOI
- https://doi.org/10.3389/fneur.2025.1599501
- Primary Topic
- Coenzyme Q10 studies and effects
- Type
- article
- Field-Weighted Citation Impact
- 0.00