Predictive accuracy of diagnostic tests for excessive bleeding in cardiac surgery: The <scp>COPTIC</scp> ‐C study
The addition of biomarkers of multimorbidity and biological aging yielded only small improvements in model predictive accuracy for bleeding over tests of coagulation. Existing clinical definitions of bleeding likely represent heterogeneous phenotypes and disease mechanisms.
Authors
- Hardeep Aujla (ORCID: https://orcid.org/0000-0002-5823-848X)
- Andrew Mumford (ORCID: https://orcid.org/0000-0002-5523-511X)
- Weiqi Liao (ORCID: https://orcid.org/0000-0002-8605-3749)
- Florence Lai (ORCID: https://orcid.org/0000-0003-4354-0624)
- Marcin Woźniak (ORCID: https://orcid.org/0000-0001-5676-8076)
- Laura Green (ORCID: https://orcid.org/0000-0003-4063-9768)
- Gavin J. Murphy (ORCID: https://orcid.org/0000-0003-0976-1482)
- Robert Grant (ORCID: https://orcid.org/0000-0002-7002-5700)
- Hasmukh Patel
Institutions
- NHS Blood and Transplant (GB)
- University of Leicester (GB)
- Queen Mary University of London (GB)
- University of Bristol (GB)
- NIHR Bristol Cardiovascular Biomedical Research Unit (GB)
Publication Details
- Journal
- Transfusion
- Published
- 2025-10-19
- DOI
- https://doi.org/10.1111/trf.18399
- Primary Topic
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Type
- article
- Field-Weighted Citation Impact
- 0.00