Disease Burden and Treatment Pattern of Advanced or Recurrent Endometrial Cancer in Korea: A Nationwide Database (DIRECTION) Study
This study demonstrated significant variability in SACT regimen sequence, highlighting the lack of consensus on standard treatment after disease relapse. Shorter TTNT and SACT-free intervals and higher HCRU and costs in later lines indicate worsening prognosis and increasing disease burden. These findings suggest the urgent need for more effective treatments, including new therapeutic agents, to address the unmet clinical needs of advanced/recurrent EC patients.
Authors
- Se Ik Kim (ORCID: https://orcid.org/0000-0002-9790-6735)
- Che‐Hun Jung (ORCID: https://orcid.org/0000-0001-7330-6295)
- Kyoung-Eun Kwon
- Young‐Kyun Lee (ORCID: https://orcid.org/0000-0001-6564-4294)
- M Bae (ORCID: https://orcid.org/0009-0009-7532-2016)
- JiYoon B. Ahn (ORCID: https://orcid.org/0000-0001-7302-0828)
- Hyun‐Woong Cho (ORCID: https://orcid.org/0000-0002-0724-9971)
- Kidong Kim
Institutions
- Korea University Medical Center (KR)
- Seoul National University Hospital (KR)
- Seoul National University Bundang Hospital (KR)
- IQVIA (United Kingdom) (GB)
- The Genetics Society of Korea (KR)
- IQ Solutions (US)
Publication Details
- Journal
- Cancer Research and Treatment
- Published
- 2025-10-20
- DOI
- https://doi.org/10.4143/crt.2025.065
- Primary Topic
- Endometrial and Cervical Cancer Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00