Continuation of Statins after Acute Intracerebral Haemorrhage and Survival: The Role of Inflammation, Infection, and Indication Bias

Exposure to statins (vs. none) after ICH was associated with lower odds of death at 30 days after adjustment for confounders. Available inflammatory markers, urinary tract infections, and pneumonia did not mediate this association. Indication bias is likely to have contributed to the association observed between statins and mortality in prior studies.

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Publication Details

Journal
Cerebrovascular Diseases
Published
2025-10-19
DOI
https://doi.org/10.1159/000549054
Primary Topic
Intracerebral and Subarachnoid Hemorrhage Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Continuation of Statins after Acute Intracerebral Haemorrhage and Survival: The Role of Inflammation, Infection, and Indication Bias

Nicole Bramhall, Adrian Parry‐Jones, Caroline Drake, Calvin Heal et al.
Cerebrovascular Diseases
Intracerebral and Subarachnoid Hemorrhage Research
article

Continuation of Statins after Acute Intracerebral Haemorrhage and Survival: The Role of Inflammation, Infection, and Indication Bias

Nicole Bramhall, Adrian Parry‐Jones, Caroline Drake, Calvin Heal, Paul R. Kasher, Hiren Patel, Justin Yeung, Firas Elfourtia
article en

Abstract

Exposure to statins (vs. none) after ICH was associated with lower odds of death at 30 days after adjustment for confounders. Available inflammatory markers, urinary tract infections, and pneumonia did not mediate this association. Indication bias is likely to have contributed to the association observed between statins and mortality in prior studies.

Cerebrovascular Diseases
Manchester Academic Health Science Centre (GB), Salford Royal NHS Foundation Trust (GB), University of Manchester (GB), King's College Hospital NHS Foundation Trust (GB), Salford Royal Hospital (GB)
Openalex Percentile: Top 58%
Intracerebral and Subarachnoid Hemorrhage Research
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Continuation of Statins after Acute Intracerebral Haemorrhage and Survival: The Role of Inflammation, Infection, and Indication Bias — Nicole Bramhall, Adrian Parry‐Jones, et al. · Cerebrovascular Diseases (2025) | TGRS Research Map | TGRS