Preoperative serum prolactin as a predictor of endocrine outcomes in nonfunctioning pituitary adenoma surgery: revisiting the "stalk effect"
Preoperative hyperprolactinemia in patients with NFPA is associated with higher risks of specific perioperative endocrinological dysfunction and pronounced pituitary stalk deviation. These findings highlight the utility of preoperative prolactin levels as a biomarker for predicting postoperative endocrinological outcomes, potentially enhancing risk assessment and guiding personalized perioperative management.
Authors
- Fredric B. Meyer (ORCID: https://orcid.org/0000-0002-4310-7962)
- Dana Erickson
- Sukwoo Hong (ORCID: https://orcid.org/0000-0002-3664-9245)
- Justine Herndon (ORCID: https://orcid.org/0000-0001-5665-0617)
- Ramin A. Morshed (ORCID: https://orcid.org/0000-0001-8464-6041)
- Irina Bancos (ORCID: https://orcid.org/0000-0001-9332-2524)
- Miguel Sáez-Alegre (ORCID: https://orcid.org/0000-0002-3903-2726)
- Jamie J. Van Gompel (ORCID: https://orcid.org/0000-0001-8087-7870)
- Sandhya Rupa Palit (ORCID: https://orcid.org/0009-0001-4639-2148)
- Diane Mary Donegan (ORCID: https://orcid.org/0000-0001-5091-9582)
- Yuki Shinya (ORCID: https://orcid.org/0000-0003-0097-5804)
- Carlos Pinheiro‐Neto (ORCID: https://orcid.org/0000-0003-3921-4658)
- John L. D. Atkinson
Institutions
- Mayo Clinic (US)
- University of Tokyo Hospital (JP)
- Mayo Clinic in Arizona (US)
- Mayo Clinic in Florida (US)
Publication Details
- Journal
- Journal of neurosurgery
- Published
- 2025-10-18
- DOI
- https://doi.org/10.3171/2025.5.jns243206
- Primary Topic
- Pituitary Gland Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00