Sevoflurane suppresses LPS-induced microglia injury by regulating USP11-mediated UHRF1 deubiquitination
Sevo could protect LPS-induced HMC3 cell apoptosis, inflammation, and oxidative stress by regulating the USP11/UHRF1 axis, which might provide a novel therapeutic mechanism for Sevo in SCI.
Authors
- Dongzhi Liu
- Xiuli Zhang (ORCID: https://orcid.org/0000-0001-5280-3049)
- Shunheng Gao
- Chengliang Sun
Institutions
- The First People’s Hospital of Lianyungang (CN)
Publication Details
- Journal
- Regenerative Therapy
- Published
- 2025-10-18
- DOI
- https://doi.org/10.1016/j.reth.2025.09.004
- Primary Topic
- Anesthesia and Neurotoxicity Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00