Metal‐Free Organophotocatalyzed Trifluoroethylation/Esterification of Alkenes
Abstract A metal‐free, organophotocatalyzed three‐component reaction between alkenes, 2,2,2‐trifluoroiodoethane, and carboxylic acids was developed. This protocol simultaneously introduces a trifluoroethyl group and an ester moiety in a single step. Preliminary mechanistic studies suggest the reaction proceeds via a radical pathway.
Authors
- Can Zeng (ORCID: https://orcid.org/0000-0002-8039-4809)
- Xiangqing Zhang (ORCID: https://orcid.org/0000-0001-7273-6170)
- Yao‐Fu Zeng (ORCID: https://orcid.org/0000-0003-2133-378X)
- Yue Wang (ORCID: https://orcid.org/0000-0002-4639-3714)
- Fang Han (ORCID: https://orcid.org/0000-0002-1937-4710)
Institutions
- Second People Hospital of Hunan (CN)
- University of South China (CN)
Publication Details
- Journal
- Asian Journal of Organic Chemistry
- Published
- 2025-10-18
- DOI
- https://doi.org/10.1002/ajoc.70232
- Citations
- 1
- Primary Topic
- Fluorine in Organic Chemistry
- Type
- article
- Field-Weighted Citation Impact
- 0.79