ARNT2-driven transcriptional activation of STRA6 reprograms fatty acid metabolism to promote retroperitoneal liposarcoma progression
This study identifies ARNT2 as a transcriptional modulator of fatty acid metabolism pathways, highlighting its potential as a viable molecular target for RLPS therapy.
Authors
- Lin Yang (ORCID: https://orcid.org/0000-0002-7594-3770)
- Xuqi Li (ORCID: https://orcid.org/0000-0002-2497-020X)
- Jie Lian (ORCID: https://orcid.org/0000-0003-3538-7746)
- Kai Deng (ORCID: https://orcid.org/0009-0002-5835-0823)
- Junxiang Zhang (ORCID: https://orcid.org/0000-0002-8406-249X)
- Guangming Li (ORCID: https://orcid.org/0000-0002-0281-8258)
- Shufeng Wang (ORCID: https://orcid.org/0000-0002-0310-1849)
- Hainan Guo (ORCID: https://orcid.org/0000-0003-1344-4172)
- He Jiang (ORCID: https://orcid.org/0000-0002-2376-6688)
- Bo Ban
- Lindi Cai
Institutions
- Shanxi Medical University (CN)
- Shaanxi Provincial People's Hospital (CN)
- First Affiliated Hospital of Xi'an Jiaotong University (CN)
- Shanxi Provincial People’s Hospital (CN)
Publication Details
- Journal
- Journal of Cancer Research and Clinical Oncology
- Published
- 2025-10-18
- DOI
- https://doi.org/10.1007/s00432-025-06352-1
- Primary Topic
- Cancer, Lipids, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.00