A Quality Improvement Pilot to Increase Hepatitis B Screening and Optimize Patient Selection for the Switch to Two-Drug Antiretroviral Regimens in People With HIV
HBV reactivation risk may be overlooked by clinicians when people with HIV switch to 2DRs. In this study, an EHR-based intervention increased HBV screening rates and decreased switches in those at highest risk of HBV reactivation (positive HBsAg or isolated positive HBcAb). With the increasing uptake of 2DRs, optimizing patient selection is vital to prevent HBV reactivation.
Authors
- Antonio Urbina (ORCID: https://orcid.org/0000-0002-3961-1007)
- Douglas T. Dieterich (ORCID: https://orcid.org/0000-0001-7786-8594)
- Michael P. Mullen (ORCID: https://orcid.org/0000-0003-1185-4389)
- Shilpa Vasishta (ORCID: https://orcid.org/0000-0002-6182-6960)
- Melissa J. Margolis (ORCID: https://orcid.org/0000-0002-6548-7273)
- Rachel Chasan (ORCID: https://orcid.org/0000-0002-5032-5490)
- Judith A. Aberg (ORCID: https://orcid.org/0000-0001-8162-0284)
Institutions
- Montefiore Medical Center (US)
- Columbia University Irving Medical Center (US)
- Icahn School of Medicine at Mount Sinai (US)
Publication Details
- Journal
- Open Forum Infectious Diseases
- Published
- 2025-09-29
- DOI
- https://doi.org/10.1093/ofid/ofaf638
- Primary Topic
- Hepatitis C virus research
- Type
- article
- Field-Weighted Citation Impact
- 0.00