Testing the Immunomodulatory Effects of Probiotic Bacillus coagulans SNZ 1969® in Healthy Adults: A Randomized, Double-Blind, Placebo-Controlled Trial
<i>B. coagulans</i> SNZ 1969<sup>®</sup> supplementation significantly enhanced NK cell activity and mucosal IgA production in adults, suggesting its potential role in strengthening the innate immune defense mechanisms. These findings support the role of <i>B. coagulans</i> SNZ 1969<sup>®</sup> as a safe dietary supplement for augmenting innate cellular immune function and thereby potentially contributing to a reduced trend to infection susceptibility; however, these preliminary findings require more extensive investigation in a larger study population.
Authors
- Kishan PV (ORCID: https://orcid.org/0000-0002-7189-5812)
- Raunak J Soman
- Dilip Soman (ORCID: https://orcid.org/0000-0001-5998-4153)
Institutions
- Veterans Health Administration (US)
- Tanvir Hospital (IN)
Publication Details
- Journal
- Cureus
- Published
- 2025-10-18
- DOI
- https://doi.org/10.7759/cureus.94845
- Primary Topic
- Probiotics and Fermented Foods
- Type
- article
- Field-Weighted Citation Impact
- 0.00