Strawberry Tongue Associated With Epstein-Barr Virus Infection in a Seven-Year-Old Boy: A Case Report

Strawberry tongue is classically associated with Kawasaki disease and scarlet fever, but it may also occur in other infectious or toxin-mediated conditions. We report a seven-year-old boy who presented with nasal obstruction, a generalized erythematous rash, and a strawberry tongue. He was afebrile and had no lymphadenopathy, hepatosplenomegaly, or pharyngeal exudate. Laboratory tests revealed mild liver enzyme elevation and a negative rapid antigen test for Group A <i>Streptococcus</i>. Serology confirmed primary Epstein-Barr virus (EBV) infection. No treatment was given, and all findings resolved spontaneously within 10 days of presentation. Although a causal relationship cannot be firmly established, careful exclusion of other etiologies supports EBV infection as the most plausible explanation for the development of strawberry tongue. This case highlights that EBV should be considered in the differential diagnosis of strawberry tongue when typical features of more common causes are absent.

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Publication Details

Journal
Cureus
Published
2025-10-18
DOI
https://doi.org/10.7759/cureus.94844
Primary Topic
Oral Health Pathology and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Strawberry Tongue Associated With Epstein-Barr Virus Infection in a Seven-Year-Old Boy: A Case Report

Masazumi Miyahara, Kyoko Osaki
Cureus
Oral Health Pathology and Treatment
article

Strawberry Tongue Associated With Epstein-Barr Virus Infection in a Seven-Year-Old Boy: A Case Report

Masazumi Miyahara, Kyoko Osaki
article en

Abstract

Strawberry tongue is classically associated with Kawasaki disease and scarlet fever, but it may also occur in other infectious or toxin-mediated conditions. We report a seven-year-old boy who presented with nasal obstruction, a generalized erythematous rash, and a strawberry tongue. He was afebrile and had no lymphadenopathy, hepatosplenomegaly, or pharyngeal exudate. Laboratory tests revealed mild liver enzyme elevation and a negative rapid antigen test for Group A <i>Streptococcus</i>. Serology confirmed primary Epstein-Barr virus (EBV) infection. No treatment was given, and all findings resolved spontaneously within 10 days of presentation. Although a causal relationship cannot be firmly established, careful exclusion of other etiologies supports EBV infection as the most plausible explanation for the development of strawberry tongue. This case highlights that EBV should be considered in the differential diagnosis of strawberry tongue when typical features of more common causes are absent.

CureusVol. 17(10)
South Okanagan General Hospital (CA)
Openalex Percentile: Top 68%
Oral Health Pathology and Treatment
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